Gastrointestinal Cancer Research Findings
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Findings from SCRUM-Japan GI-SCREEN Study and GOZILA Study

For patients with gastrointestinal cancer, the SCRUM-Japan GI-SCREEN study and GOZILA study showed that Guardant360® assay can be an alternative to standard of care tissue biopsy with a higher sample success rate and that patients enrolled with Guardant360® achieved similar clinical outcomes as patients enrolled with tissue testing1.

Guardant360® assay can be an alternative to standard of care tissue biopsy with a higher sample success rate1

99.9% success rate

GC_Table_5

99.9% success rate

Patients enrolled with Guardant360® achieved similar clinical outcomes as patients enrolled with tissue testing1

  • The objective response rate (ORR) for patients enrolled by plasma or by tissue-based testing and treated with targeted therapy was 20% versus 16.7%, respectively.
  • The median progression-free survival (PFS) for patients enrolled by plasma or by tissue-based testing and treated with targeted therapy was 2.4 months versus 2.8 months, respectively.

Reference:
1.
Nakamura Y, Taniguchi H, Ikeda M, et al. Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies. Nat Med. 2020 Dec;26(12):1859-1864. doi: 10.1038/s41591-020-1063-5

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